Fluorescent Carbon Dot-Supported Imaging-Based Biomedicine: A Comprehensive Review

Le Minh Tu Phan 1 and Sungbo Cho 2,3
1. School of Medicine and Pharmacy, e University of Danang, Danang 550000, Vietnam
2. Department of Electronic Engineering, Gachon University, Seongnam, Gyeonggi-do 13120, Republic of Korea
3. Department of Health Sciences and Technology, GAIHST, Gachon University, Incheon 21999, Republic of Korea
Correspondence should be addressed to Le Minh Tu Phan; plmtu@smp.udn.vn and Sungbo Cho; sbcho@gachon.ac.kr
Received 3 September 2021; Revised 27 September 2021; Accepted 17 March 2022; Published 10 April 2022
Academic Editor: Songwen Tan
Copyright © 2022 Le Minh Tu Phan and Sungbo Cho. )is is an open access article distributed under the Creative Commons
Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Carbon dots (CDs) provide distinctive advantages of strong fluorescence, good photostability, high water solubility, and outstanding biocompatibility, and thus are widely exploited as potential imaging agents for in vitro and in vivo bioimaging. Imaging is absolutely necessary when discovering the structure and function of cells, detecting biomarkers in diagnosis, tracking the progress of ongoing disease, treating various tumors, and monitoring therapeutic efficacy, making it an important approach in modern biomedicine. Numerous investigations of CDs have been intensively studied for utilization in bioimaging-supported medical sciences. However, there is still no article highlighting the potential importance of CD-based bioimaging to support various biomedical applications. Herein, we summarize the development of CDs as fluorescence (FL) nanoprobes with different FL colors for potential bioimaging-based applications in living cells, tissue, and organisms, including the bioimaging of various cell types and targets, bioimaging-supported sensing of metal ions and biomolecules, and FL imaging-guided tumor therapy. Current CDbased microscopic techniques and their advantages are also highlighted. )is review discusses the significance of advanced CDsupported imaging-based in vitro and in vivo investigations, suggests the potential of CD-based imaging for biomedicine, and encourages the effective selection and development of superior probes and platforms for further biomedical applications.

Link trang: Fluorescent Carbon Dot-Supported Imaging-Based Biomedicine: A Comprehensive Review (hindawi.com)

Link file PDF: 2022_ BCA_Fluorescent Carbon Dot-Supported Imaging-Based Biomedicine A Comprehensive Review

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